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Since it re-rolls every item in the room it can be more efficient to use it in rooms where multiple items are in the same room. If Isaac has no Red Heart containers items can be bought for three Soul Hearts Black Hearts.


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Upon use replaces every item in the current room not pickups or trinkets with other random items corresponding to the current rooms item pool.

. Occasionally items may cost Soul Hearts even if Isaac still has Red Hearts. The Devil Room pool is the pool of items that can be found in the Devil Room. Isaac starts with this item once it is unlocked.

All items can be bought for some number of Red Heart containers. Any items outside of the Devil Room item pool will have a price of 1. The D6 is an unlockable activated item.

The D6 is a special item.


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